Alzheimer’s drug may be promising treatment for traumatic brain injury


There is some promising research results for treatment of patients with traumatic brain injury. Treatment for Traumatic Brain Injury (TBI) is often elusive. While it's a major cause of disability and death, finding treatment with medications has generally failed. A new study found that memantine, a drug that is used to treat dementia associated with Alzheimer's disease, may be a promising therapy.

The study examined the effect of the drug on blood levels of neuron­specific enolase (NSE), a marker of neuronal damage. The blood level was significantly reduced by day 7 of treatment.

In addition, the Glasgow Coma Scale (GCS) is commonly used after a brain injury to describe the level of consciousness in a person following a traumatic brain injury. There were marked improvements in traumatic brain injury patients GCS by day 3 of treatment in the study.

Source:
http://newsroom.wiley.com/press­release/journal­clinical­pharmacology/ alzheimers­drug­may­help­treat­traumatic­brain­injury

Nutrition Research Update: Eating Fruit May Lower Risk for Type 2 Diabetes


Eating certain whole fruits may reduce the risk for type 2 diabetes, according to a research study reported by the Harvard School of Public Health. The study reviewed the reports of over 187,000 long-term Nurse’s Health Study and the Health Professionals Follow-up Study members’ diets.

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Blueberries, grapes and raisins, apples and pears, bananas, grapefruit are all beneficial in preventing many chronic diseases, including Type 2 Diabetes. The study results revealed that for every 3 servings of fruit eaten per week, there was a lower risk for type 2 diabetes.

The studies also revealed that drinking fruit juice instead of whole fruits may actually increase the risk for diabetes.

Whole Fruit or fruit juice? The effect on blood sugar can be explained by digestion. Cantaloupe and fruit juice are considered to have a low glycemic load. Most whole fruit have a high glycemic load. The glycemic index is a measure of how foods and liquids affect blood sugar and insulin. The lower a food’s glycemic index or glycemic load, the less it affects blood sugar and insulin levels. Keeping blood sugar at a steady state reduces the risk for diabetes and the complications of diabetes.

The results of the study show that eating a variety of whole fruits, especially blueberries, grapes, and apples, are useful for preventing diabetes.

Medical Research Findings: Today and Tomorrow Can be Vastly Different


Isn’t science a wonderful thing? Because of medical research, our life expectancy has changed dramatically. In 1900, the average life expectancy for a man was 47 years of age! Today it is 77 and getting older as we speak.

Medical research has allowed a death sentence for people diagnosed with HIV in 1982 to now become a chronic illness for the vast majority of those diagnosed since 1995. Cancer of the breast and prostate most often lead to death in in the 1960’s. Today, the degree of the cancer determines survival. The lower the degree, better the survival rate.

Yesterday I reported that social, mental and physical activity to counteract loneliness helps to decrease the likelihood of developing dementia. Today, new research indicates that physical activity helps reduce the risk of Vascular dementia, but not Alzheimer’s dementia.

These reports can become pretty confusing. You may feel as though your head is spinning. So what are you to believe?

Research reports are as good as the design and execution of the study. It is impossible for lay people to scrutinize every piece of information they hear and determine whether or not it is sound research.

Only time can really tell what will hold water in research results. While learning the results of studies is helpful, looking at the data is important to a physician, nurses, and other allied health professionals. Ask your health care provider to explain things that you hear that are pertinent to you.

Using common sense is helpful along the way. Consider the example of exercise. Does exercise help keep a person healthy? Scientific research is showing that, yes, it does. In years past, people were thinner because they did work that required alot more physical effort compared to most jobs today. Facts show that most adults in previous times did not develop diabetes. Diabetes was seen mostly in children who acquired it from a genetic or immune disorder.

Today, twenty percent of all adults age 60 years and older develop diabetes. Thirty(30%) percent of older adults who are obese have diabetes as compared to 13% of their thinner counterparts.

At least 10 million Americans at high risk for type 2 diabetes can sharply lower their chances of getting the disease with diet and exercise, according to the findings of a major clinical trial at the National Institutes of Health (NIH). All of the people enrolled in this study participated in lifestyle changes with diet and exercise which reduced their risk for developing diabetes. About 15% developed diabetes within 3 years of this study. Not reported in the short report was how many continued with the lifestyle changes.

I reported early in this blog that a new study reported that exercise will help reduce the risk for vascular dementia. So why talk about diabetes? People who exercise less often have a higher risk of developing diabetes. Diabetes causes complications in the blood vessels. Vascular dementia is one of these comlications. Vascular dementia is caused by a change in the blood flow in the vessels of the brain, causing cell death. Cell death in the brain causes dementia.

A tangled web or a domino effect? Lifestyle factors play a huge role. Balance in how many aspects of life impact health overall: stress level, social interaction, sleep, diet, exercise and physical activity level are all predictors of health. This is the overall theme to learn from current medical research findings. What we learn today, the changes in lifestyle made today, can effect our health tomorrow.